解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Fluoride is a well-studied and widely used agent for the prevention of dental caries. Although dental caries is strongly related to cariogenic biofilms, the effect of brief fluoride treatment on the virulence properties of biofilms has not been well studied. This study evaluated the effect of a 1-min fluoride treatmen...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000434731
更新日期:2015-01-01 00:00:00
abstract::Early childhood caries (ECC) is closely related to high numbers of mutans streptococci, lactobacilli and Candida albicans. Oral colonization of these microorganisms was monitored in a prospective clinical study in order to investigate the effect of comprehensive treatment under general anesthesia and the sustainabilit...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000351673
更新日期:2014-01-01 00:00:00
abstract::The aim of this study was to evaluate the accuracy of cone beam computed tomography (CBCT) in the detection of noncavitated occlusal caries lesions and to compare this accuracy with that observed with conventional radiographs. 135 human teeth, 67 premolars and 68 molars with macroscopically intact occlusal surfaces, w...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000358101
更新日期:2014-01-01 00:00:00
abstract::This study analyzed the effects of fluoride varnishes supplemented with sodium trimetaphosphate (TMP) on the remineralization of caries-like lesions in vitro. Bovine enamel discs were selected through surface hardness (SH) and caries-like lesions were induced. SH was again determined and the blocks were divided into 7...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000356308
更新日期:2014-01-01 00:00:00
abstract::Current understanding of dental caries considers this disease a demineralization of the tooth tissues due to the acid produced by sugar-fermenting microorganisms. Thus, caries is considered a diet- and pH-dependent process. We present here the first metagenomic analysis of the bacterial communities present at differen...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000351663
更新日期:2013-01-01 00:00:00
abstract::Dental caries results from an imbalance of the metabolic activity in the dental biofilm. The microbial communities of teeth have traditionally been studied by standard cultural approaches. More recently, cloning and sequencing of the 16S rRNA gene have been used to characterize the microbial composition of the oral bi...
journal_title:Caries research
pub_type: 杂志文章,评审
doi:10.1159/000345367
更新日期:2013-01-01 00:00:00
abstract:AIM:The aim of this study was to evaluate the effectiveness of partial removal of carious dentine and restoration in a single session (PDR) and stepwise excavation (SW), both of which are treatments for deep carious lesions, in Public Health Services in Brazil. METHODS: INCLUSION CRITERIA:patients ≥6 years old, perma...
journal_title:Caries research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1159/000344013
更新日期:2013-01-01 00:00:00
abstract:AIM:To assess the effect of protein-containing toothpastes on the progression of dental erosion in situ (with pellicle) and in vitro (without pellicle). METHODS:A combined split-mouth (extraoral water or toothpaste brushing) and crossover (type of toothpaste) setup was used. Two protein-containing (high/low concentrat...
journal_title:Caries research
pub_type: 杂志文章,随机对照试验
doi:10.1159/000344016
更新日期:2013-01-01 00:00:00
abstract::Dental caries is generally given the highest priority in national oral health services for school-aged populations. Yet, there is no study exploring the impacts on quality of life specifically related to dental caries in national samples of school-aged children. This study assessed prevalence and characteristics of or...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000342893
更新日期:2013-01-01 00:00:00
abstract::The mechanistic action of fluoride on inhibition of enamel demineralization was investigated using (19)F magic angle spinning nuclear magnetic resonance (MAS-NMR). The aim of this study was to monitor the fluoride-mineral phase formed on the enamel as a function of the concentration of fluoride ions [F(-)] in the demi...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000350171
更新日期:2013-01-01 00:00:00
abstract::Molar-incisor hypomineralisation (MIH) is a problematic and costly condition. Caries remineralising agents are often recommended for MIH management despite the lack of evidence that these lesions have the capacity for increasing their mineral content. Following surface layer removal ± NaOCl pre-treatment and 14-day ex...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000346134
更新日期:2013-01-01 00:00:00
abstract::This longitudinal study aimed to investigate variables associated with colonisation of mutans streptococci (MS) compared with lactobacilli (LB) colonisation in a cohort of children (n = 214) from the time of first tooth eruption at approximately 6 months until 24 months of age. Repeated plaque and salivary samples wer...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000339089
更新日期:2012-01-01 00:00:00
abstract::This study aimed to determine the reliability and accuracy of the ICDAS and radiographs in detecting and estimating the depth of proximal lesions on extracted teeth. The lesions were visible to the naked eye. Three trained examiners scored a total of 132 sound/carious proximal surfaces from 106 primary teeth and 160 s...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000324439
更新日期:2011-01-01 00:00:00
abstract::The literature on the erosive potential of drinks and other products is summarised, and aspects of the conduct of screening tests as well as possible correlations of the erosive potential with various solution parameters are discussed. The solution parameters that have been suggested as important include pH, acid conc...
journal_title:Caries research
pub_type: 杂志文章,评审
doi:10.1159/000325917
更新日期:2011-01-01 00:00:00
abstract::Metalloproteinases (MMPs) have been implicated with metabolism of collagen in physiological and pathological processes in human dentine. As bovine teeth have been used as a substitute for human teeth in laboratory analysis, this study evaluated the activity of MMP-2 and -9 in bovine versus human dentine. Bovine and hu...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000330525
更新日期:2011-01-01 00:00:00
abstract::In this study we evaluated the effect of chitosan nanoparticles on the acid tolerance response (ATR) of adhered Streptococcus mutans. An ATR was induced by exposing S. mutans to pH 5.5 for 2 h and confirmed by exposing the acid-adapted cells to pH 3.5 for 30 min, with the majority of cells appearing viable according t...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000331206
更新日期:2011-01-01 00:00:00
abstract::The aim of this study was to assess the prevalence of gastro-oesophageal reflux disease (GORD) symptoms and tooth wear in patients with Sjögren's syndrome (SS) compared with matched controls. GORD symptoms were assessed for 33 SS patients and 20 age- and sex-matched controls. Tooth wear was assessed in all patients an...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000329381
更新日期:2011-01-01 00:00:00
abstract:AIM:To evaluate how concentration and pH of TiF(4) influence the erosion-protective effect. METHODS:Specimens were treated with a TiF(4) solution: (1) 0.5 M F, pH 1.2, (2) 0.05 M F, pH 2.1, (3) 0.5 M F, pH 2.1, or (4) 0.05 M F, pH 1.2; then, they were exposed to HCl. RESULTS:After 2 min, the proportions of the area c...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000324155
更新日期:2011-01-01 00:00:00
abstract::The relationship between clinical characteristics of carious dentin and bacterial colonization after partial caries removal is not completely understood. The aim of this study was to compare microbial counts between categories of carious dentin color, consistency and humidity, and to evaluate the correlation between t...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000325854
更新日期:2011-01-01 00:00:00
abstract::In recent years a strategy of selective, symptom-based intervention of carious primary teeth has been developed amongst some British general dental practitioners. Practice-based studies appear to provide evidence that policies of restoration of symptomless carious primary teeth do not confer any significant benefits a...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000314677
更新日期:2010-01-01 00:00:00
abstract::This in vivo study aimed to evaluate the performance of methods of approximal caries detection in primary molars and to assess the influence of the discomfort caused by these methods on their performance. Two examiners evaluated 76 children (4-12 years old) using visual inspection (ICDAS), radiography and a laser fluo...
journal_title:Caries research
pub_type: 杂志文章,随机对照试验
doi:10.1159/000320266
更新日期:2010-01-01 00:00:00
abstract::Data on the prevalence of tooth wear among children and adolescents are inconsistent. Given the impact of extensive tooth wear for over a lifetime, evidence on the extent is required. The aim was to systematically review the literature on the prevalence of tooth wear in children and adolescents. A PubMed literature se...
journal_title:Caries research
pub_type: 杂志文章,评审
doi:10.1159/000308567
更新日期:2010-01-01 00:00:00
abstract:AIM:The aim of the study was to evaluate if pH indicator strips could be used for measurements of plaque pH acidogenicity in situ. METHOD:Interproximal plaque pH was measured before and up to 60 min after a 10% sucrose rinse in 30 healthy volunteers using pH indicator strips and the microtouch method in parallel. RES...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000315273
更新日期:2010-01-01 00:00:00
abstract::This study investigated the relationship of arginine deiminase (ADS) and urease activities with dental caries through a case-control study. ADS and urease activities were measured in dental smooth-surface supragingival plaque and whole saliva samples from 93 subjects, who were in three different groups: caries-free (n...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000321139
更新日期:2010-01-01 00:00:00
abstract::This paper describes the dental health status of Italian 4-year-olds in 2004/2005 and analyzes the association between caries in preschool children and some background characteristics in children and parents. Caries was recorded according to WHO criteria. 5,538 subjects were examined. Information on the children's and...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000211719
更新日期:2009-01-01 00:00:00
abstract::A total of 26 healthy volunteers participated in this randomized 4-leg crossover study designed to measure fluoride (F) retention in interdental plaque and saliva. Two NaF dentifrices (5,000 and 1,450 ppm F) were used, with and without postbrushing water rinsing. The 4 tooth brushing methods were carried out twice a d...
journal_title:Caries research
pub_type: 杂志文章,随机对照试验
doi:10.1159/000201592
更新日期:2009-01-01 00:00:00
abstract::The aim of this study was to enumerate and identify bifidobacteria from occlusal carious lesions in permanent and deciduous teeth. Samples of infected dentine were obtained from 24 active occlusal lesions in deciduous teeth and from 15 occlusal lesions in permanent teeth. Plaque samples from sound occlusal surfaces of...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000222659
更新日期:2009-01-01 00:00:00
abstract::This in vivo study aimed to compare the performance of different methods of approximal caries detection in primary molars. Fifty children (aged 5-12 years) were selected, and 2 examiners evaluated 621 approximal surfaces of primary molars using: (a) visual inspection, (b) the radiographic method and (c) a pen-type las...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000189705
更新日期:2009-01-01 00:00:00
abstract::The aim was to describe the prevalence and incidence of caries lesions in relation to the placement and replacement of amalgam and non-metal fillings in a randomly selected adult Danish population. In 1997 and in 2003, 470 individuals underwent a full-mouth radiographic survey. All recordings were based on radiographs...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000217861
更新日期:2009-01-01 00:00:00
abstract::This study evaluated, by cross-sectional hardness (CSH), enamel maturation at different depths in sound human teeth at different posteruptive ages (12 per age group): unerupted (molars; control), 2-3 years (premolars), 4-10 years (premolars) and >10 years (molars). Cross-sectional Knoop hardness was measured at 10, 30...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000264687
更新日期:2009-01-01 00:00:00
abstract::Salivary proteins protect teeth against acid-induced softening and demineralization by forming a pellicle. However, little is known about individual, gender and ethnic variations in this effect. Therefore, we aimed to determine differences in protective effects of experimentally formed pellicles from 10 healthy young ...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000213887
更新日期:2009-01-01 00:00:00
abstract::Acidic fluoride solutions may reduce dental erosion. The aim of this study was to compare the effect of different acidic fluoride solutions on enamel dissolution using an established in vivo model. When possible 4 anterior teeth (255 teeth in a total of 67 subjects) were isolated and exposed to 0.01 M citric acid. The...
journal_title:Caries research
pub_type: 杂志文章,随机对照试验
doi:10.1159/000209345
更新日期:2009-01-01 00:00:00
abstract::The aim of the study was to determine whether rinsing with a mouthwash after brushing with a fluoridated toothpaste affected oral fluoride (F) retention and clearance compared with an oral hygiene regime without mouthwash. In this supervised, single-blind study, 3 regimes were compared: (A) brushing for 1 min with 1 g...
journal_title:Caries research
pub_type: 杂志文章,随机对照试验
doi:10.1159/000239753
更新日期:2009-01-01 00:00:00
abstract::The aim of this study was to investigate the influence of salivary macromolecules on enamel lesion remineralization in the presence or absence of fluoride. Paraffin-stimulated whole saliva was centrifuged, and the supernatant was dialyzed in 1,000 molecular-weight cutoff dialysis tubes, first against a phosphate buffe...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000111748
更新日期:2008-01-01 00:00:00
abstract::Much of the research regarding the efficacy of fluoridated milk was obtained prior to the routine use of fluoridated dentifrices. The aim was to investigate, in situ, the effect of fluoridated and non-fluoridated milk on mineral change in artificial caries lesions, with the additional use of fluoridated dentifrice. Th...
journal_title:Caries research
pub_type: 杂志文章,随机对照试验
doi:10.1159/000148163
更新日期:2008-01-01 00:00:00
abstract::Previous studies have shown that sucrose promotes changes in the composition of the extracellular matrix (ECM) of plaque-like biofilm (PLB), but its effect on protein expression has not been studied in vivo. Therefore, the protein compositions of ECM of PLB formed with and without sucrose exposure were analyzed by two...
journal_title:Caries research
pub_type: 临床试验,杂志文章
doi:10.1159/000159607
更新日期:2008-01-01 00:00:00
abstract::The influence of beverage composition on the measurement of erosive potential is unclear. The aim of this study was to evaluate whether beverage composition influences the measurement of erosive potential and to evaluate the influence of exposure in small and large volumes. Eleven beverages were included: water (contr...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000116118
更新日期:2008-01-01 00:00:00
abstract::This in situ/ex vivo study assessed the effect of different concentrations of fluoride in dentifrices on dentin subjected to erosion or to erosion plus abrasion. Ten volunteers took part in this crossover and double-blind study performed in 3 phases (7 days). They wore acrylic palatal appliances containing 4 bovine de...
journal_title:Caries research
pub_type: 杂志文章,随机对照试验
doi:10.1159/000117807
更新日期:2008-01-01 00:00:00
abstract::To study the effects of prolonged and exclusive breast-feeding on dental caries, we followed up children participating in the Promotion of Breastfeeding Intervention Trial (PROBIT), a cluster-randomized trial of a breast-feeding promotion intervention based on the WHO/UNICEF Baby-Friendly Hospital Initiative. A total ...
journal_title:Caries research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1159/000108596
更新日期:2007-01-01 00:00:00
abstract::The purpose of this study was to investigate the demineralization of dentin by measuring changes in the velocity of the sonic longitudinal waves transmitted through this substrate. One group of samples was immersed in demineralization solution for 10 min twice a day and then stored in artificial saliva. Two additional...
journal_title:Caries research
pub_type: 杂志文章
doi:10.1159/000099319
更新日期:2007-01-01 00:00:00